Personalized Gene Therapy Proposal

Proposal of Personalized Multimodal Information Diffusion System

The new Information and Communication Technologies (ICT) give the possibility to have access to huge masses of information via varied supports (PC, PDA, Cell phone). Thus, to allow the traveller to find the information he is interested in, the personalization is the appropriate solution. In this article, we will propose a Personalized Multimodal Information Diffusion System (PMIDS) based on mul...

Colorectal Cancer: Personalized Therapy.

BACKGROUND Colorectal cancer (CRC) is the second most common type of cancer in the Western world. The treatment of this disease has evolved greatly, particularly for patients with metastatic disease. The advent of combination chemotherapy plus targeted agents has led to more curative resections and improved survival rates in these patients. A deeper understanding of the mechanisms of tumorigene...

Stem cells' guided gene therapy of cancer: New frontier in personalized and targeted therapy.

INTRODUCTION Diagnosis and therapy of cancer remain to be the greatest challenges for all physicians working in clinical oncology and molecular medicine. The statistics speak for themselves with the grim reports of 1,638,910 men and women diagnosed with cancer and nearly 577,190 patients passed away due to cancer in the USA in 2012. For practicing clinicians, who treat patients suffering from a...

Toward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery

The success of lentiviral vectors in curing fatal genetic and acquired diseases has opened a new era in human gene therapy. However, variability in the efficacy and safety of this therapeutic approach has been reported in human patients. Consequently, lentiviral-vector-based gene therapy is limited to incurable human diseases, with little understanding of the underlying causes of adverse effect...

ژن درمانی Gene Therapy